Decoding the Science of Chronic Pain

icon mic

June 03, 2026

Chronic pain affects one quarter of adults globally, costing employers roughly half a trillion dollars in lost productivity, absenteeism, and healthcare costs every year.

In this episode, Dr. Sean Mackey, a pain medicine specialist at Stanford University, explains why the number of individuals experiencing chronic pain is increasing and reveals the fascinating science behind pain as "a product of the brain" shaped by not only injury but also sleep, stress, mood, and past experiences.

Dr. Mackey also outlines the six treatment categories for chronic pain which include medications, procedures, mind-body approaches, physical rehabilitation, alternative medicines, and self-empowerment through education. He shares how psychological factors like anxiety and poor sleep can negatively impact surgical outcomes and offers practical advice for those seeking effective pain care.

We wrap up with emerging research on precision pain medicine, including biomarkers and "digital twin" technology, plus a lightning round dispelling common pain myths.

SPEAKERS

Sean Mackey, MD, PhD | Chief of the Division of Pain Medicine at Stanford University

LuAnn Heinen | Business Group on Health

Download Transcript

Duration 35 min

Subscribe To The Podcast

All Podcasts

Showing items 21-30 of 127
Aug 11, 2025
What You Say and How You Say It: How A Positive...
Dr. Jonathan Adler explains the science behind personal storytelling and how your "narrative identity” has the power to shape your...
Read more
Jul 28, 2025
Addressing the Overlooked Epidemic in Men’s Health
Men’s health is facing a silent crisis, with rising deaths of despair, widening life expectancy gaps and too few conversations...
Read more
Jul 14, 2025
High Hopes for Healing: Exploring Cannabis Therapy
Cannabis use is rising fast, but research lags behind. Dr. Ziva Cooper explains the risks, benefits and urgent need for better...
Read more
Jun 30, 2025
“Eat, Gobble, and Go:” Unpacking American Food...
Convenience, customization and “snackification” reign supreme in American food culture. Author Sophie Egan explains U.S. eating...
Read more
Jun 10, 2025
Working with Cancer: Helping Employers Support...
Cancer survivor Gina Jacobson shares how working during treatment was vital to her healing process and how that experience...
Read more
May 12, 2025
‘Tune in’ to Well-being with the Healing Power of...
Neurobiologist, Dr. Daniel Bowling, unpacks music and sound’s therapeutic potential for conditions like depression, anxiety, ADHD...
Read more
Apr 28, 2025
Social Prescribing for Purpose, Connection and...
Journalist Julia Hotz explores social prescribing—when health care professionals prescribe social activities like art...
Read more
Apr 08, 2025
The Missing Billion: Reducing Health Barriers for...
Explore disability health disparities, inclusive care strategies and the potential for AI to improve health care accessibility...
Read more
Mar 24, 2025
Revisiting Alcohol Use: Risks, Trends and Recovery
Examine the connection between alcohol and cancer, rising trends and recovery strategies with experts John Kelly and Rachel Sayko...
Read more
Feb 10, 2025
Truth and Lies: How Historical Biases Shape...
Historical biases in medicine continue to shape women’s health care today. Dr. Elizabeth Comen explores how these misconceptions...
Read more
Showing items 21-30 of 127